Grace / Synthetech

Company Description


Grace specializes in materials-based, value-added solutions for the pharmaceutical process manufacturing industry. Grace’s Synthetech product line provides contract manufacturing services in organic synthesis, biocatalysis, and chiral technologies. The product offering also includes specialty amino acids, peptide building blocks and fragments, and proprietary custom chiral intermediates primarily for the pharmaceutical, biotech, and cosmeceutical industries. The Synthetech products support the development and manufacture of therapeutic peptides, peptidomimetic, and small molecule drugs at every stage of the clinical development pipeline; including regulatory starting materials and advanced intermediates; from grams to tons. Grace also manufactures Syloid® FP silica, a multi-functional excipient which has unique properties that improve handling, adsorption, dissolution and delivery of pharmaceutical compounds. In addition, Grace offers products for pilot and process scale purification, including Davisil® and Vydac® chromatographic media, MODcol® flanged and Spring® dynamic axial compression preparative and process columns, and Multipacker® column packing stations. With manufacturing sites in Europe, North America, South America and Asia, and experience in regulatory and quality compliance, Grace is well positioned to support the needs of global pharmaceutical companies with local service and expertise. For the full offering of Grace solutions for process manufacturing, please visit our website at

Chemical Services Directory

Click on arrows below to expand each category.

Reactions Directory/Types of Chemistries

  • Acetylation
  • Acid Chloride Synthesis
  • Acylation
  • Alkylation
  • Amidation
  • Benzoylation
  • Bromination
  • Carboxylation
  • Chiral Chemistry
  • Chlorination
  • Condensation
  • Coupling
  • Cyclization
  • Dehydration
  • Dehydrogenation
  • Dehydrohalogenation
  • Diazotization
  • Diels-Alder Reaction
  • Elimination
  • Enzymatic Reactions
  • Epoxidation
  • Esterification
  • Etherification
  • Fluorination
  • Formylation
  • Freidel-Crafts Reaction
  • Grignards
  • Halogenation
  • Hydroboration
  • Hydrobromination
  • Hydrochlorination
  • Hydrogenation
  • Hydrohalogenation
  • Hydrolysis
  • Imidization
  • Iodination
  • Isomerization
  • Methylation
  • n-Alkylation
  • Nitration
  • Organo-Metallic Chemistry
  • Oxidation
  • Rearrangements
  • Reduction
  • Reductive Alkylation
  • Reformatsky Reaction
  • Resolution
  • Ring Closing Metathesis
  • Substitution
  • Sulfurization
  • Transesterification
  • Ullman Reaction
  • Wittig Reaction

Capabilities/Services Directory

  • Biocatalysis
  • Continuous Processing
  • Custom Manufacturing
  • Custom Synthesis
  • Distillation
  • Organic Synthesis
  • Peptide Synthesis

Manufacturing/Toll Capacities

  • Bench/Lab Scale
  • Commercial Scale
  • Kilo Scale

Industries / Markets Served

  • Pharmaceutical
  • Specialty Chemicals


  • Centrifuges
  • Dryers
  • Filters
  • Reactors » Batch » Jacketed
  • Waste Management Equipment


  • cGMP
  • ChemStewards
  • ChemStewards » Excellence Tier Site
  • OHSAS 18001

Performance Improvement Awards

  • 2013 Bronze Award
  • 2010 Gold Performance Award


  • Specialty Amino Acids
  • Peptide Fragments
  • Chiral Intermediates
  • Organometallics
  • Boronic Acids

SOCMA Member Plant(s)

  • W.R. Grace & Co. - Conn. (Albany Plant) , Albany , Oregon , United States

More Company Information

Business Opportunities

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Announcements & Resource Library

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Innovations Posters

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